Nā huahana

Hoʻohana ka hana ʻana o ka p-hydroxyacetophenone i ka phenol ma ke ʻano he mea maka, a loaʻa iā ia e ka acylation a me ka transposition.Hoʻohui i ka phenol a me ka acetyl chloride, wela mālie a hiki i ka hoʻokuʻu ʻia ʻana o ka hydrogen chloride e hoʻomākaukau i ka phenyl acetate, e hoʻohui i ka nitrobenzene, e hoʻohui i ka alumini trichloride ma hope o ka hoʻoluʻu ʻana, e hoʻoulu i nā hola 2-3, a laila e ninini i ka wai anuanu, e hoʻohui i ka 1: 3 hydrochloric acid a hiki i He mea maʻalili, extract me ka etera, distill ka etera mai ka extract, distill nitrobenzene a me ka hua o-hydroxyacetophenone ma ka mahu distillation, a waiho i ka p-hydroxyacetophenone i ke koena.Loaʻa ka huahana ma o ka unuhi ʻana a me ka recrystallization.

[Hana Hana Hana] Nā huahana upstream phenol, acetyl chloride, a me p-hydroxyacetophenone.Nā huahana lalo: 4-quinoxalinyl-2-phenol, N-acetaminophen, 4-hydroxystyrene, atenolol, 3'-chloromethyl-4'-hydroxyacetophenone, 4-benzyl Oxy-3-nitroacetophenone, p-hydroxyphenethyl alcohol, 1-{4- (acetoxy)-3-[(acetoxy)methyl]phenyl}-2-bromoethanone, 2- (Benzyl-tert-butylamino) -4'-hydroxy-3'-hydroxymethylacetophenone diacetate hydrochloride, 4-acetoxystyrene.