Nā huahana

Loaʻa nā huahana PO i nā hopena anti-dandruff a me nā anti-itching, kū hoʻokahi anti-dandruff mechanical, solubility maikaʻi a me ka hui hou ʻana, palekana, non-toxic, non-irritating, a hoʻohana nui ʻia i ka shampoo a me nā huahana mālama lauoho.Loaʻa ka PO i nā hopena antipruritic maikaʻi loa, a loaʻa pū kekahi i ka sterilization a me nā hana deodorization, no laila ua hoʻohana ʻia i nā lotions ʻauʻau e hoʻokō i nā hopena maikaʻi.Loaʻa i ka PO kahi hopena pepehi ākea ākea i nā fungi a me nā mold, a he hopena therapeutic maikaʻi ma ka wāwae a me ka ringworm lima.Hiki ke hoʻohana ʻia ma ke ʻano he preservative i nā mea hoʻonaninani, ma ke ʻano he bactericide i ke kopa, a ma ke ʻano he mānoanoa.No laila, ʻo PO he multifunctional anti-dandruff a antipruritic bactericide, i hoʻohana nui ʻia i ka shampoo a me nā huahana mālama lauoho, nā wai ʻauʻau, nā mea hoʻonaninani, a me nā mea holoi.

ʻO Piroctone olamine, ka paʻakai ethanolamine o ka hydroxamic acid derivative Piroctone, he mea hana anti-mycotic hydroxypyridone.Hoʻokomo ʻo Piroctone olamine i ka membrane cell a hana i nā paʻakikī me nā ion hao, ke kāohi nei i ka metabolism ikehu i ka mitochondria [1].ʻO Piroctone olamine (PO) he paʻakai ethanolamine o ka hydroxamic acid derivative Piroctone.Hōʻike nā kānana Candida āpau i nā haʻahaʻa haʻahaʻa haʻahaʻa haʻahaʻa (MICs) no Piroctone olamine (0.125-0.5 μg/mL) a me Amphotericin B (AMB) (0.03-1 μg/mL).

Ke manaʻo nei kēia hana e loiloi i ka hana antifungal o Piroctone olamine i ka mālama ʻana i ka candidiasis intra-abdominal ma kahi hoʻohālike hoʻokolohua e hoʻohana ana i nā ʻiole Swiss.Hana ʻia ka mālama ʻana me Piroctone olamine (0.5 mg/kg) i 72 mau hola ma hope o ka maʻi ʻana e ka intraperitoneal administration.No ka hoʻohālikelike, mālama ʻia kahi hui o nā holoholona (n=6) me Amphotericin B (0.5 mg/kg).Hana ʻia ka maʻi mycological ma o ka ʻohi ʻana i ke ake, spleen a me nā puʻupaʻa.Hoʻopili ʻia nā ʻikepili e pili ana i ka ulu ʻana o ka fungal a me ka make ʻana ma ka helu helu e ka hoʻāʻo t a ka haumāna a me ka nānā ʻana o ka ʻokoʻa, me ka pae o ke koʻikoʻi i kau ʻia ma P<0.05.He mea koʻikoʻi ka ʻokoʻa o ka ulu ʻana o ka fungal ma waena o ka pūʻulu hoʻomalu a me nā hui mālama (Piroctone olamine a me Amphotericin B) (P<0.05)